Vitamin A Overdose – Side Effects, Symptoms & Treatment

Health Care Guide on Vitamin A overload Amount, death effects, Symptoms in Children & Pregnancy with Treatment & Medication 


Hypervitaminosis A

Excessive intake of vitamin A affect:-

  • CNS : headache, nausea, ataxia, anorexia, increased intracranial CSF pressure.
  • Liver : hepatomegaly with histologic changes and hyperlipidemia.
  • Calcium hemeostasis : thickening of long bones, hypercalcemia and calcification of soft tissues.
  • Skin : excessive dryness, desquamation and alopecia.
  • Mucous membrane defects

Toxicity is very unlikely with normal sources, but must be taken into account when prescribing high doses of retinoic acid for severe acne sufferers. Sufficiently high doses of vitamin A can cause mucous metaplasia of keratinizing epithelium.


Pregnant women must not take more than 3.3mg/day because vitamin A excess causes congenital defects. Therefore, they must avoid vitamin A supplements or eating liver because it contains about 13-40 mg of vitamin A per 100g. Parental administration of vitamin A for treatment of acne is absolutely contraindicated in pregnancy.

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