Manganese as Mineral – Rich Food Sources, Functions, Deficiency & Daily Requirements for Children, Men & Women

Presentation Notes on Manganese (Mn) Vegetarian & Non Vegetarian Food Sources, Recommended Dietary Allowance, Cobalt deficiency disorders, Role in Human Body with Treatment & Toxicity in word / .doc / .ppt format

Manganese:

The total body content of manganese is about 30 mg.

Daily requirement:

  • Adults: 2-5 mg.
  • Children: 0.5-2.0 mg.

Sources:

  • Cereals,
  • Vegetables
  • Live
  • Kidney
  • Muscle
  • tea

Functions:

  • Acts as a cofactor for enzymes such as arginase, isocitrate dehydrogenase, leucine aminopeptidase. Manganese-containing enzymes are hydrolases, kinases, decarboxylases and transferases. It is a cofactor for mitochondrial superoxide dismutase.
  • Role in animal reproduction. Deficiency causes sterility in animals and disturbance in citric acid cycle.
  • Proteoglycan synthesis. Promotes synthesis and deposition of proteoglycan in many tissues including bones due to glycosyltransferase activity.
  • Porphyrin synthesis. Some porphyrins of erythrocytes contain manganese.
  • Bone growth and cholesterol synthesis require manganese.

Absorption, transport and excretion:

  • Absorbed from gut.
  • Miners absorb manganese dust through lungs.
  • Transported in combination with b-globulin called transmanganin.
  • Stored in liver.
  • Little is excreted in urine.
  • Excreted mainly through bile and faeces.

Clinical manifestations:

Deficiency results in the following symptoms :

  • Defective growth in mammals and birds.
  • Respiratory dysfunction.
  • Disturbance in lipid metabolism.
  • Hypoglycemia, poor bone growth and lactation problems.

Toxicity:

  • Miners show encephalitis.
  • Impotence, psychosis and extra pyramidal syndrome (EPS) seen.


Download More Information on Manganese as Mineral

No comments:

Post a Comment